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HOME＞研究報告＞2008年度以降　長崎大学歯学部「再生工学研究」

２００８年度以降　長崎大学歯学部「再生工学研究」
 
２０１１年
  1. Moriishi T, Maruyama Z, Fukuyama R, Ito M, Miyazaki T, Kitaura H, Ohnishi H,
    Furuichi T, Kawai Y, Masuyama R, Komori H, Takada K, Kawaguchi H, Komori T. Overexpression of Bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis. PLoS ONE. 2011, in press.
  2. Wang Y, Liu W, Masuyama R, Fukuyama R, Ito M, Zhang Q, Komori H, Murakami T, Moriishi T, Miyazaki T, Kitazawa R, Yoshida CA, Kawai Y, Izumi S, Komori T. Pyruvate dehydrogenase kinase 4 induces bone loss at unloading by promoting osteoclastogenesis. Bone. 2011 Jul 23. [Epub ahead of print]
  3. Maeno T, Moriishi T, Yoshida CA, Komori H, Kanatani N, Izumi S, Takaoka K, Komori T. Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation,and limb defects. Bone. 49(4): 673-682. 2011.
  4. Cao L, Moriishi T, Miyazaki T, Iimura T, Hamagaki M, Nakane A, Tamamura Y, Komori T, Yamaguchi A. Comparative morphology of the osteocyte lacunocanalicular system in various vertebrates. J Bone Miner Metab. 2011 Apr 19. [Epub ahead of print]
  5. Hisa I, Inoue Y, Hendy GN, Canaff L. Kitazawa R, Kitazawa S, Komori T, Sugimoto T, Seino S, Kaji H. Parathyroid Hormone-responsive Smad3-related Factor, Tmem119, Promotes Osteoblast Differentiation and Interacts with the Bone Morphogenetic Protein-Runx2 Pathway. J Biol Chem. 286(11): 9787-9796. 2011.
  6. Ann EJ, Kim HY, Choi YH, Kim MY, Mo JS, Jung J, Yoon JH, Kim SM, Moon JS, Seo MS, Hong JA, Jang WG, Shore P, Komori T, Koh JT, and Park HS. Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation. J Bone Miner Res. 26(2): 317-330, 2011.
  7. Komori T. Signaling networks in RUNX2-dependent bone development. J Cell Biochem. 112(3): 750-755, 2011.
  8. Suehiro F, Nishimura M, Kawamoto T, Kanawa M, Yoshizawa Y, Murata H, Kato Y.
    Impact of zinc fingers and homeoboxes 3 on the regulation of mesenchymal stem cell osteogenic differentiation. Stem Cells Dev. 20(9): 1539-1547, 2011.

２０１０年
  1. Watanabe K, Sugai M, Nambu Y, Osato M, Hayashi T, Kawaguchi M, Komori T, Ito Y, Shimizu A. Requirement for Runx proteins in IgA class switching acting downstream of TGF-{beta}1 and retinoic acid signaling. J Immunol. 184(6): 2785-2792, 2010.
  2. M. Mikasa, S. Rokutanda, H. Komori, K. Ito, Y. Tsang, Y. Date, C. A. Yoshida, and T. Komori. Regulation of Tcf7 by RUNX2 in chondrocyte maturation and proliferation. J Bone Miner Metab. 29(3): 291-299, 2010.
  3. Komori T. Regulation of osteoblast differentiation by Runx2. Adv Exp Med Biol. 658:43-49, 2010
  4. T.Komori. Regulation of osteoblast and odontoblast differentiation by RUNX2. J Oral Biosci. 52: 22-25, 2010
  5. Komori T. Regulation of bone development and extracellular matrix protein genes by RUNX2. Cell Tissue Res. 339(1):189-195, 2010
  6. Ikeda H, Sumita Y, Ikeda M, Ikeda H, Okumura T, Sakai E, Nishimura M, Asahina I.
    Engineering Bone Formation from Human Dental Pulp- and Periodontal Ligament-Derived Cells. Ann Biomed Eng. 2010 Jul 8. [Epub ahead of print]
  7. Sumita Y, Honda MJ, Ueda M, Asahina I, Kagami H Differential effects of growth differentiation factor-5 on porcine dental papilla- and follicle-derived cells. Growth Factors. 28(1) 56-65, 2010.
  8. Kato R, Iejima D, Agata H, Asahina I, Okada K, Ueda M, Honda H, Kagami H. A Compact, Automated Cell Culture System for Clinical Scale Cell Expansion from Primary Tissue. Tissue Eng Part C Methods. 2010 Jan 30

２００９年
  1. S.Rokutanda, T.Fujita, N.Kanatani, CA.Yoshida, H.Komori, W.Liu, A.Mizuno and T.Komori. Akt regulates skeletal development through GSK3, mTOR, and FoxOs. Dev. Biol. 328(1):78-93, 2009.
  2. J.Sakamoto, T.Origuchi, M.Okita, J.Nakano, K.Kato, T.Yoshimura, S.Izumi, T.Komori, H.Nakamura, H.Ida, A.Kawakami, and K.Eguchi. Immobilization-induced cartilage degeneration mediated through expression of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and chondromodulin-I. Connect Tissue Res. 50(1):37-45, 2009.
  3. Uchida M, Agata H, Shinohara N, Kagami H, Ueda M, Asahina I. Mixing conditions for cell scaffolds affect the bone formation induced by bone engineering with human bone marrow stromal cells, beta-tricalcium phosphate granules, and rhBMP-2. J Biomed Mater Res A. 9(1) 84-91 2009
  4. Agata H, Asahina I, Watanabe N, Ishii Y, Kubo N, Ohshima S, Yamazaki M, Tojo A, Kagami H. Characteristic change and loss of in vivo osteogenic abilities of human bone marrow stromal cells during passage. Tissue Eng Part A. 2009 Sep 15.e-pub

２００８年
  1. T.Miyazaki, N.Kanatani, S.Rokutanda, C.Yoshida, S.Toyosawa, R.Nakamura, S.Takada, and T.Komori. Inhibition of terminal differentiation of odontoblasts and their transdifferentiation into osteoblasts in Runx2 transgenic mice. Arch.Histol.Cytol. 71:131-146,2008
  2. T.Tanaka, H.Sato, H.Doi, CA.Yoshida, T.Shimizu, H.Matsui, M.Yamazaki, H.Akiyama, K.Kawai-Kowase, T.Iso, T.Komori, M.Arai, and M.Kurabayashi. Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells. Mol Cell Biol. 28(3):1147-60, 2008
  3. T.Komori. Regulation of bone development and maintenance by Runx2. Front Biosci. 13:898-903, 2008
  4. Masuyama R, Vriens J, Voets T, Karashima Y, Owsianik G, Vennekens R, Lieben L, Torrekens S, Moermans K, Vanden Bosch A, Bouillon R, Nilius B, Carmeliet G. TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts. Cell Metab. 8:257-265, 2008.

 
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