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  長崎大学重点研究課題「骨格系の基盤研究拠点形成」
長崎大学歯学部歯周病基盤研究センター
 
 
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HOME研究報告>2010年度「口腔環境制御研究」報告:北海道大学歯学部

2010]年度「口腔環境制御研究」報告: 北海道大学歯学部
 
<口腔分子微生物学教室>
  1. Mu HH, Hasebe A, Van Schelt A, Cole BC. Novel interactions of a microbial   superantigen with TLR2 and TLR4 differentially regulate IL-17 and Th17-associated   cytokines. Cell Microbiol 13(3): 374-387, 2011.
  2. Donen M, Ohtani M, Kiura K, Saeki A, Tanizume N, Hasebe A, Totsuka Y, Shibata K. Relationship of expression and function of Toll-like receptor 2 and 4 with aging in human   and mouse. Hokkaido J Dent Sci 31(2), 82-89, 2010.
  3. Into T, Inomata M, Niida S, Murakami Y, Shibata K. Regulation of MyD88 Aggregation and the MyD88-dependent Signaling Pathway by Sequestosome 1 and Histone Deacetylase 6. J Biol Chem 285: 35759-33576, 2010.
  4. Shamsul HM, Hasebe A (MSH and AH, equal contribution), Iyori M, Ohtani M, Kiura K, Zhang D, Totsuka Y, Shibata KI. The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36   but not by TLR2. Immunology 130: 262-272, 2010.
  5. Into T, Inomata M, Shibata K, Murakami Y. Effect of the antimicrobial peptide LL-37 on Toll-like receptors 2-, 3- and 4-triggered expression of IL-6, IL-8 and CXCL10 in human gingival fibroblasts. Cell Immunol 264: 104-109, 2010.
  6. Takeshi Nishioka Motoaki Yasuda Tsuguhide Takeshima, Hisashi Haga, Yusuke    Miyai, Ken-ichiro Shibata, Rie Yamazaki, Hiroki Shirato, Masahiro Teduka, and Hiroyuki Date. Radiation-induced Cancer Cell Repopulation: A Possible Mechanism Implied by Experiments Using Transplantable Mouse-derived Sarcoma Cell Line. Cell Struct Func 36: 13–20, 2011.

<口腔病理病態学教室>
  1. Obinata K, Sato T, Ohmori K, Shindo M, Nakamura M: A comparison of diagnostic tools for Sjogren syndrome, with emphasis on sialography, histopathology, and ultrasonography. Oral Surg Oral Med Oral Pahtol Oral Radiol Endod, 109:129-134, 2010.
  2. Sato J, Notani K-I, Goto M, Shindoh M, Kitagawa Y: Synovial chondromatosis of the temporomandibular joint accompanied by loose bodies in both the superior and inferior joint compartments: case report. Int J Oral Maxillofac Surg, 39:86-88, 2010.
  3. Kakuguchi W, Kitamura T, Kuroshima T, Ishikawa M, Kitagawa Y, Totsuka Y, Shindoh M, Higashino F: HuR knockdown changes the oncogenic potential of oral cancer cells. Mol Cancer Res, 8:520-528, 2010.
  4. Matsuda K, Ohga N, Muraki C, Kurosu T, Tsuchiya K, Akino T, Shih SC, Totsuka Y, Klagsbrun M, Shindoh M, Hida K: Isolated tumor endothelial cells maintain specific character during long-term culture. Biochem Biophys Res Commun, 394:947-954, 2010.
  5. Tsuchiya K, Hida K, Hida Y, Muraki C, Ohga N, Akino T, Kondo T, Miseki T, Nakagawa K, Shinbdoh M, Harabayashi T, Shinohara N, Nonomura K, Kobayashi M: Adrenomedullin antagonist suppresses tumor formation in renal cell carcinoma through inhibitory effects on tumor endothelial cells and endothelial progenitor mobilization.  Int J Oncol, 36:1379-1386, 2010.
  6. Higashino F, Hida K, Kitamura T, Ohga N, Shindoh M: Aberrant control of transcription and translation of oncogeneic mRNA in carcinogenesis. Oral Sci Int, 7:11-18, 2010.
  7. Hida K, Ohga N, Kurosu T, Totsuka Y, Shindoh M: Crosstalk between blood vessels and tumor microenvironment. Oral Sci Int, 7:1-10, 2010.
  8. Satoh K, Tsukamoto M, Shindoh M, Totsuka Y, Oda T, Matsumoto K:  Increased expression of Tenascin-X in thoracic and abdominal aortic aneurysm tissues.    Biol Pharm Bull. 33:1898-1902, 2010.
  9. Hassan NMM, Tada M, Shindoh M, Hamada J-I, Kashiwazaki H, Shimo Y, Yamazaki Y, Sasaki a, Moriuchi T, Inoue N: Multiple primary carcinomas including leukoplakia and SCC: A report with p53 mutation analysis. Anticancer Res, 30:4773-4778, 2010.
  10. Nitta Y, Hida K, Kitamura T, Higashino F, Fukushima K, Shindoh M: The phenotype of tumor lymphatic vessels could be a prognostic factor in human tongue squamous cell carcinoma. Oncol Lett, 2:79-83, 2011.
  11. Kurosu T, Ohga N, Hida Y, Maishi N, Akiyama K, Kakuguchi W, Kuroshima T, Kondo M, Akino T, Totsuka Y, Shindoh M, Higashino F, Hida K: HuR keeps on angiogenic switch on by stabilizing mRNA of VEGF and COX-2 in tumor endothelium. Br J Cancer, 104:819-829, 2011.
  12. Kuroshima T, Aoyagi M, Yasuda M, Kitamura T, Jehung JP, Ishikawa M, Kitagawa Y, Totsuka Y, Shindoh M, Higashino F: Viral mediated stabilization of AU-rich element containing mRNA contributes to cell transformation.  Oncogene in press, 2011.
  13. Muraki C, Ohga N, Hida Y, Nishihara H, Kato Y, Tsuchiya K, Matsuda K, Totsuka Y, Shindoh M, Hida K: Cyclooxygenase-2 inhibition causes antiangiogenic effects on tumor endothelial and vascular progenitor cells. Int J Cancerin press, 2011.

<口腔機能解剖学教室>
  1. 髙橋 茂、井上貴一朗、舩橋 誠、土門卓文. 北海道大学全学教育科目「唾液のサイエンス」におけるクリッカー使用とその効果の検討、北海道歯誌31:75-81、2010.
  2. Hanaizumi Y, Yokoya R, Domon T, Wakita M, Kozawa Y. Initial process of enamel prism   arrangement and its relation to the Hunter-Schreger bands in dog teeth. Arch Histol Cytol 73: 23-36, 2010.

細胞分子薬理学教室
  1. Waleed El-Beialy, Nadia Galal, Yoshiaki Deyama, Yoshitaka Yoshimura, Kuniaki Suzuki , Kanchu Tei, Yasunori Totsuka. Effects of estrogenon PMCA 2 and 4 in human fibroblast- like synovial cells and mouse macrophage-like cells. End J 57(1): 93-97, 2010.
  2. Waleed El-Beialy, Nadia Galal, Yoshiaki Deyama, Yoshitaka Yoshimura, Kuniaki Suzuki , Kanchu Tei, Yasunori Totsuka. Regulation of human and pig renal Na,K-ATPase activity by tyrosine phosphorylation of their a-1 subunits. J Mem Biol 233 : 119-126, 2010.
  3. Hajime Minamikawa, Masahiro Yamada1, Fuminori Iwasa, Takeshi Ueno, Yoshiaki      Deyama, Kuniaki Suzuki , Yasutaka Yawaka , and Takahiro Ogawa. Amino acid    derivative-mediated detoxification and functionalization of dual cure dental restorative    material for dental pulp cell mineralization. Biomaterials 31(28):7213-7225, 2010.
  4. 石川一郎、出山義昭、吉村善隆、鈴木邦明. フッ素による アルミニウムに依存した    Na,K-ATPase活性の抑制. 北海道歯学雑誌,31(2): 44-51, 2011.
  5. 野呂洋輔、大廣洋一、鄭 漢忠、吉村善隆、出山義昭、飯塚 正、鈴木邦明、 戸塚    靖則(2011. 家兎下顎骨骨 空洞の治癒過程におけるPLGA・コラーゲ ン・ハイブリ    ッドメッシュの有用性の検討.北海道歯学雑誌,31(2): 62-69, 2011. 

硬組織発生生物学教室
  1. Kii I, Nishiyama T, Li M, Matsumoto KI, Saito M, Amizuka N, Kudo A.: Incorporation of tenascin-C into the extracellular matrix by periostin underlies an extracellular meshwork   architecture. J Biol Chem 285(3):2028-39, 2010.

 
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